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decarboxylate

/ˌdiːkɑːrˈbɒksɪleɪt/ verb · British & US
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What does decarboxylate mean?

Decarboxylate refers to the chemical process of removing a carboxyl group (-COOH) from a molecule. This reaction is fundamental in biochemistry, particularly in metabolic pathways such as the synthesis of neurotransmitters and the breakdown of amino acids. The process involves the elimination of carbon dioxide (CO2) and results in the formation of a new compound with distinct properties. Decarboxylation reactions are catalyzed by specific enzymes called decarboxylases and play a critical role in various physiological and biochemical processes. Understanding decarboxylation is essential for insights into metabolic regulation, drug development, and the study of diseases related to metabolic dysfunctions.

verb

To remove a carboxyl group from a molecule, typically through a chemical reaction. This process is a key step in various biochemical pathways.

Senses
  1. To remove a carboxyl group from a molecule.
  2. A biochemical reaction involving decarboxylation.
Example

"The enzyme decarboxylated the amino acid, converting it into a neurotransmitter."

More examples

"The decarboxylation of amino acids is crucial for neurotransmitter synthesis."

"In organic chemistry, decarboxylation reactions are common and important."

Reviewed by Deb Chak, Editor. AI-assisted content curated by RJS Tech Solutions LLP.

Etymology of decarboxylate

The term 'decarboxylate' originates from the prefix 'de-', meaning 'removal of', and 'carboxyl-', referring to the carboxyl group. The suffix '-ate', used in chemistry to form names of salts and esters, is also present. The word is derived from the concept of removing a carboxyl group, which is a fundamental process in organic and biochemistry.

Usage notes

Formal or technical contexts, especially in biochemistry, organic chemistry, and related fields.

Synonyms for decarboxylate

Rhymes with decarboxylate